Isaiah 1:15

And when ye spread forth your hands
That is, in prayer, this being a prayer gesture: hence the Targum paraphrases it,

``and when the priests spread out their hands to pray for you.''

I will hide mine eyes from you;
will not look upon them, nor regard their prayer; see ( Lamentations 3:42 ) yea, when ye make many prayers;
as the Scribes and Pharisees did in Christ's time, and thought to be heard for their much speaking, like the Gentiles, ( Matthew 6:7 ) I will not hear;
so as to give an answer, or fulfil their requests: the reason follows, your hands are full of blood;
of the prophets of the Lord, of Christ and his followers, whom they put to death.